Mycoplasma infections are relatively common in laboratory cell cultures; it has been estimated that between 5% and 35% of all cell cultures are infected. Mycoplasma are the smallest and simplest prokaryotes. Mycoplas...
The transfection grade polyethylenimine (PEI) is a powerful, trusted, and cost-effective reagent widely considered as a current gold standard for both in vitro and in vivo transfection. PEI h...
Polyethylenimine (PEI) is a synthetic cationic polymer with high charge density and chain flexibility. It is the most widely investigated cationic polymer for non-viral delivery of nucleic acids. Linear PEI can be an effe...
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms. Roughly one to two residues of 5-methylcytidine occur in every 1,000 RNA...
N1-Methylpseudouridine is a modified nucleoside used for enhancing mRNA translation. Incorporation of N1-Methylpseudouridine into mRNA turns off the immune/eIF2α phosphorylation-dependent inhibition of translat...
Methoxypolyethylene glycol carboxyl (mPEG-COOH) are high quality PEG reagents that attach a reactive carboxyl (COOH) group at the terminal site, which can selectively reacts with amino group in the peptide coupling r...
Base modified NTPs have been widely used for synthesis of modified mRNA to improve stability and reduce immunogenicity.
ABP Biosciences offers a list of key base modified NTPs for mRNA synthesis.
C...
5-Methyl-CTP (5-Methylcytidine-5'-Triphosphate) is a modified nucleoside triphosphate employed to impart desirable characteristics such as increased nuclease stability, increased translation or reduced interaction of ...
Pseudo-UTP (Pseudouridine-5'-Triphosphate) is one of the most commonly used modified nucleoside-5’-O-triphosphates. Pseudo-UTP is a building block for the polymerase-mediated synthesis of RNA molecules. RNA mole...
N1-Methylpseudo-UTP (N1-Methyl-Pseudouridine-5'-Triphosphate) is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenici...
Lipid Nanoparticles (LNPs) play important role for delivery of mRNA-based vaccines.
ABP Biosciences offers a list of key lipids for formulation of Lipid Nanoparticles (LNPs).
Lipid
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LNP-0315 is a lipid nanoparticle (LNP) formulated with ALC-0315, DSPC, Cholesterol, and ALC-0159. LNP-0315 is formulated at optimal molar ratio for efficient delivery of mRNA-based vaccines.
L...
LNP-102 is a lipid nanoparticle (LNP) formulated with SM-102, DSPC, Cholesterol, and DMG-PEG2000. LNP-102 is formulated at optimal molar ratio for efficient delivery of mRNA-based vaccines.
LNP-102...
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral phospholipid containing 18:1 fatty acids at the sn–1 and sn–2 positions. The compound displays sensitivity towards pH change. At acid...
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn–1 and sn–2 positions. It has been used in combination...
DMG-PEG(2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Formulations containing DMG-PEG(2000) have been used in the development of lipid ...
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons. It is a&...
ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). ALC-0315 has been used in the development of lipid nanoparticles for delivery of mRN...
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). SM-102 has been used in the development of lipid nanoparticles for delivery of mRNA-ba...
The newly identified coronavirus, SARS-CoV-2 (2019-nCoV), has become one of the most contagious disease in human history.
ABP Biosciences offers essential reagents and tools for your exciting coron...
DNAzol BD Reagent is a reagent specifically formulated for the isolation of genomic DNA from whole blood. The DNAzol BD Reagent is based on the use of a novel guanidine- detergent lysing solution which hydrolyzes RNA and all...
DNAzol Reagent is a complete and ready-to-use reagent for the isolation of genomic DNA from solid and liquid samples of animal, plant, yeast, and bacterial origin. The DNAzol Reagent is a novel guanidine-detergent lysing sol...
RNAzol BD Reagent is a ready-to-use reagent, designed to isolate total RNA, large RNA or small RNA from whole blood, plasma or serum of human or animal origin. The RNA can be used for RNA sequencing and gene expression analy...
Exosomes are small vesicles (50-120 nm in diameter) containing proteins, DNA/RNA and lipids, actively secreted by exocytosis in most living cells.
ABP Biosciences offers a wide selection of exosome isolation reagents...
iScript™ IV TaqProbe One-Step RT-qPCR Kit is a complete qPCR system containing all necessary reagents for both reverse transcription and TaqMan Probe based qPCR amplification to occur in a single reaction qPCR reaction...
iScript™ IV One-Step RT-PCR Kit contains all necessary reagents for both reverse transcription and PCR amplification to occur in a single reaction tube. RT-PCR Enzyme Mix (10X) contains iScript™ IV Reverse Transc...
iScript™ IV Reverse Transcriptase (RT) is a novel recombinant reverse transcriptase that exhibits much higher efficiency in the first-strand cDNA synthesis from RNA templates with secondary structures and high GC conte...
iScript™ IV Reverse Transcriptase (RT) is a novel MMLV mutant with superior robustness and reliability in RT reactions. It exhibits much higher efficiency in the first strand cDNA synthesis from RNA templates with seco...
ABP's iScript™ IV Reverse Transcriptase is engineered to work under high temperatures (50°C-55°C), which can further facilitate to resolve the secondary structures and high GC problems of RNA.
ABP offers...
The HotStart Taq DNA Polymerase is a chemically modified Taq DNA Polymerase, whose enzyme activities can only be activated after 3-5 minutes of incubation at 94oC. The HotStart Taq Polymerase uses amplification conditions fo...
Taq DNA polymerase is purified from E. coli. expressing a cloned Thermus aquaticus DNA polymerase gene. Taq DNA Polymerase is a thermostable enzyme that synthesizes DNA from single-stranded templates in the presence of ...
ABP dNTP Set is a convenient set of 100 mM aqueous solutions of each of dATP, dCTP, dGTP and dTTP, supplied in separate vials. The solutions of these extremely stable nucleotides are titrated to pH 7.3-7.5 with NaOH. The nuc...
ABP dNTP Mix contains premixed aqueous solutions of dATP, dCTP, dGTP and dTTP, each at a final concentration of 10 mM. The nucleotides have greater than 99% purity, are free of nuclease activities, human and E. coli DNA. Mix...
ABP HotStart Taq PCR Master Mix is a 2× concentrated solution of HotStart Taq DNA Polymerase, dNTPs, and all of the components required for PCR, except DNA template and primers. HotStart Taq PCR Master Mix pr...
ABP Taq PCR Master Mix is a 2× concentrated solution of Taq DNA Polymerase, dNTPs, and all of the components required for PCR, except DNA template and primers. Taq PCR Master Mix provides robust and reliable ...
The newly identified coronavirus, SARS-CoV-2 (2019-nCoV), belongs to the Betacoronavirus Genus, which also includes SARS CoV (2003) and MERS CoV (2012). The genome of SARS-CoV-2 (2019-nCoV) encodes t...
RNAlater Reagent stabilizes and protects cellular RNA in intact, unfrozen tissue samples, eliminating the need to immediately process tissue samples or to freeze samples in liquid nitrogen for later processing. Tissue pieces...
RNAzol RT Reagent is a ready-to-use reagent, designed to isolate high quality total RNA and small RNA from samples of human, animal, plant, bacterial and viral origin. RNAzol RT Reagent is a monophasic solution of phenol, gu...
TRIzol LS Reagent is a ready-to-use reagent, designed to isolate high quality total RNA (as well as DNA and proteins) from a variety of liquid samples. TRIzol LS Reagent is a monophasic solution of phenol, guanidine isothioc...
TRIzol Reagent is a ready-to-use reagent, designed to isolate high quality total RNA (as well as DNA and proteins) from cell and tissue samples of human, animal, plant, yeast, or bacteria origin. TRIzol Reagent is a monophas...
ExoFast™ Exosome Isolation Reagent from other body fluids enables fast and efficient enrichment of intact exosomes from cerebrospinal fluid (CSF), ascitic fluid, amniotic fluid, milk, and saliva with a protocol that is...
ExoFast™ Exosome Isolation Reagent from urine enables fast and efficient enrichment of intact exosomes from urine samples.
Advantages:
Maximize recovery of intact exosomes for any type of downs...
ExoFast™ Exosome Isolation Reagent from plasma enables fast and efficient enrichment of intact exosomes from plasma samples.
Advantages:
Maximize recovery of intact exosomes for any type of dow...
ExoFast™ Exosome Isolation Reagent from serum enables fast and efficient enrichment of intact exosomes from blood serum samples.
Advantages:
Maximize recovery of intact exosomes for any ty...
ExoFast™ Exosome Isolation Reagent from cell culture media enables fast and efficient enrichment of intact exosomes from cell culture media samples.
Advantages:
Maximize recovery of intact...
ABP HiFi DNA Polymerase is a new generation superior enzyme based on Pfu DNA Polymerase for robust PCR with extreme fidelity. High amplification efficiency and template adaptability makes ABP HiFi DNA Polymerase suitabl...
ABP HiFi DNA Polymerase is a new generation superior enzyme based on Pfu DNA Polymerase for robust PCR with extreme fidelity. High amplification efficiency and template adaptability makes ABP HiFi DNA Polymerase suitabl...
Mycoplasma infections are relatively common in laboratory cell cultures; it has been estimated that between 5% and 35% of all cell cultures are infected. Mycoplasmas have been shown to alter the growth rate of cells in cultu...
Mycoplasma infections are relatively common in laboratory cell cultures; it has been estimated that between 5% and 35% of all cell cultures are infected. Mycoplasmas have been shown to alter the growth rate of cells ...
Mycoplasma infections are relatively common in laboratory cell cultures. Mycoplasmas have been shown to alter the growth rate of cells in culture, induce chromosomal aberrations, influence amino acid and nucleic acid...