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5-Methyl-CTP (5-Methylcytidine-5'-Triphosphate) is a modified nucleoside triphosphate employed to impart desirable characteristics such as increased nuclease stability, increased translation or reduced interaction of innate immune receptors with in vitro transcribed RNA. 5-Methyl-CTP, as well as Pseudo-UTP and N1-Methylpseudo-UTP, have been shown to reduce innate immune stimulation in culture and in vivo while enhancing translation in recent publications. 

For research use only.


Technical Information

Formal Name: 5-Methylcytidine-5'-Triphosphate
CAS Number: 327174-86-7 (free acid)
Molecular Formula: C10H18N3O14P3 (free acid)
Molecular Weight: 497.18 (free acid)
Purity: >95% (HPLC)
Extinction Coefficient: 8,800 Lmol-1cm-1 at 277 nm
Salt Form: Na+
Concentration: 100 mM in H2O
Storage Condition: -20 ℃
Shipping Condition: Ice packs

To order

Buy Cat.No. Product name Size Price
LP011-1 5-Methyl-CTP 10 µL $90
LP011-2 5-Methyl-CTP 50 µL $400
LP011-3 5-Methyl-CTP 100 µL $740


Product Information (PDF): LP011

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