Home » Reactive Dyes » QSY7 Quencher, Succinimidyl Ester

 

QSY7 Quencher, Succinimidyl Ester

Introduction

QSY7 quencher succinimidyl ester is a nonfluorescent acceptor dye for preparation of peptide and oligonucleotide FRET probes.


Features

  • Fluorescence quantum yields <0.001 in aqueous solution;
  • Absorption spectra of the conjugates are insensitive to pH between 4 and 10;
  • Efficient quenching of the fluorescence emission of donor dyes including blue-fluorescent coumarins, green- or orange-fluorescent dyes, and red-fluorescent Texas Red conjugates;
  • Quenching of most green and red fluorophores is more effective at far greater distances than is possible with dabcyl quenchers.


Specifications

Reactivity: Primary amine
Abs maximum: 560 nm
Extinction coefficient: 90,000 cm-1M-1
Solubility: DMSO, DMF
Molecular Formula: C43H39ClN4O7S
Molecular Weight: 791.32
CAS Number: 304014-12-8
Storage Conditions: -20 ℃, protect from light
Shipping Condition: Room Temperature

Applications

FRET probe.

To order

Buy Cat.No. Product name Size Price
C100 QSY7 Quencher, SE 5 mg $160

Documents

Datasheet (PDF): C100
MSDS (PDF): MSDS-C100

References:

A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape.

Douek DC, Betts MR, Brenchley JM, Hill BJ, Ambrozak DR, Ngai KL, Karandikar NJ, Casazza JP, Koup RA
J Immunol (2002) 168:3099-3104


Actin filament uncapping localizes to ruffling lamellae and rocketing vesicles.

Allen PG
Nat Cell Biol (2003) 5:972-979


Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.

Shi XP, Tugusheva K, Bruce JE, Lucka A, Wu GX, Chen-Dodson E, Price E, Li Y, Xu M, Huang Q, Sardana MK, Hazuda DJ
J Biol Chem (2003) 278:21286-21294