5-Ethynyl-dUTP (5-EdUTP) (cat. no. C432) is supplied as a 1 mM solution in TE buffer.
5-EdUTP can be enzymatically incorporated into DNA with Reverse Transcriptases, Taq DNA Polymerase, phi29 DNA Polymerase, Klenow Fragm...
The transfection grade polyethylenimine (PEI) is a powerful, trusted, and cost-effective reagent widely considered as a current gold standard for both in vitro and in vivo transfection. PEI h...
Polyethylenimine (PEI) is a synthetic cationic polymer with high charge density and chain flexibility. It is the most widely investigated cationic polymer for non-viral delivery of nucleic acids. Linear PEI can be an effe...
Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moieties to label and detect a molecule of interest in mild, aqueous conditions. DBCO alkynes can be used to perform clic...
Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moieties to label and detect a molecule of interest in mild, aqueous conditions. DBCO alkynes can be used to perform clic...
Luciferins are a class of ATP-dependent substrates that are oxidized in the presence of the enzyme luciferase to produce oxyluciferin and energy in the form of light. Luciferin undergoes an enzyme-catalysed oxidation and ...
Luciferins are a class of ATP-dependent substrates that are oxidized in the presence of the enzyme luciferase to produce oxyluciferin and energy in the form of light. Luciferin undergoes an enzyme-catalysed oxidation and ...
MitoTrack™ Deep Red FM (Known as MitoTracker® Deep Red FM, Trade Mark of ThermoFisher Scientific) is a Near IR-fluorescent dye that stains mitochondria in live cells and its accumulation is dependent upon...
MitoTrack™ Red FM (Known as MitoTracker® Red FM, Trade Mark of ThermoFisher Scientific) is an red-fluorescent dye that stains mitochondria in live cells and its accumulation is dependent upon membrane potentia...
MitoTrack™ Green FM (Known as MitoTracker® Green FM, Trade Mark of ThermoFisher Scientific) is an green-fluorescent dye that stains mitochondria in live cells and its accumulation is dependent upon membrane potenti...
JC-9 Dye is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-9 exists as a monomer at low concentrations and yields green fluorescence, similar to fluorescein. A...
Andy Fluor 647 Tyramide is used in tyramide signal amplification (TSA), a method for high-density labeling of a target protein or nucleic acid in situ. This reagent can be used with any antibody conjugated to HRP for tyramid...
Andy Fluor 594 Tyramide is used in tyramide signal amplification (TSA), a method for high-density labeling of a target protein or nucleic acid in situ. This reagent can be used with any antibody conjugated to HRP for tyramid...
Andy Fluor 555 Tyramide is used in tyramide signal amplification (TSA), a method for high-density labeling of a target protein or nucleic acid in situ. This reagent can be used with any antibody conjugated to HRP for tyramid...
Andy Fluor 488 Tyramide is used in tyramide signal amplification (TSA), a method for high-density labeling of a target protein or nucleic acid in situ. This reagent can be used with any antibody conjugated to HRP for tyramid...
Tyramide signal amplification (TSA) is a highly sensitive method enabling the detection of low-abundance targets in fluorescent immunocytochemistry (ICC), immunohistochemistry (IHC), and in situ hybridization (F...
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms. Roughly one to two residues of 5-methylcytidine occur in every 1,000 RNA...
N1-Methylpseudouridine is a modified nucleoside used for enhancing mRNA translation. Incorporation of N1-Methylpseudouridine into mRNA turns off the immune/eIF2α phosphorylation-dependent inhibition of translat...
Methoxypolyethylene glycol carboxyl (mPEG-COOH) are high quality PEG reagents that attach a reactive carboxyl (COOH) group at the terminal site, which can selectively reacts with amino group in the peptide coupling r...
The mitochondrion plays a vital role in the processes of apoptotic and necrotic cell death. The mitochondrial permeability transition pore is a nonspecific channel formed by components from the inner and outer mitochondrial ...
The mitochondrion plays a vital role in the processes of apoptotic and necrotic cell death. The mitochondrial permeability transition pore is a nonspecific channel formed by components from the inner and outer mitochondrial ...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
The MitoSOX Red Indicator is a fluorogenic dye for the highly selective detection of superoxide in the mitochondria of live cells. The MitoSOX Red reagent is live-cell permeant which rapidly and selectively target th...
The iQuant™ microRNA Assay Kit is ideal for quantification of small RNA, including microRNA and siRNA, and both single stranded and double stranded RNA. The assay kit is highly selective for small RNA over rRNA or...
2-NBDG is a fluorescent glucose analog that has been used to monitor glucose uptake in live cells, as an indicator of cell viability. Although sensitive to its environment NBD fluorescence typically displays excitati...
Blunt/TA Ligase Master Mix is a ready-to-use 2× solution, which is specifically formulated to improve ligation and transformation of both blunt-end and single-base overhang substrates. The master mix format simplifies ...
The Quick T4 DNA Ligation Kit enables ligation of cohesive end or blunt end DNA fragments in 15 minutes at room temperature.
Applications
Routine subcloning.
Recircularization of linear DNA.
Library const...
T4 DNA Ligase catalyzes the formation of a phosphodiester bond between 5’-phosphate and 3’-hydroxyl termini in duplex DNA or RNA. The enzyme repairs single-strand nicks in duplex DNA, RNA or DNA/RNA hybrids, join...
PolyFectRNA™ Transfection Reagent is an innovative cationic nanotechnology developed specifically for the delivery of siRNA and miRNA into a wide range of eukaryotic cells. PolyFectRNA™ Transfection Reagent provi...
PolyFectVIR™ Transfection Reagent is an innovative cationic nanotechnology developed for the gene and cell therapy field to improve virus production. This ready-to-use chemically defined reagent is guaranteed free of c...
Benzonase Nuclease is a genetically engineered endonuclease from Serratia marcescens. It degrades all forms of DNA and RNA (single stranded, double stranded, linear and circular) while having no proteolytic activity. It is e...
T4 β-glucosyltransferase (T4 BGT) is a DNA-modifying enzyme encoded by bacteriophage T4 that catalyzes the transfer of glucose (Glc) from uridine diphosphoglucose (UDP-Glc) to 5-hydroxymethylcytosine (5-hmC) residues in...
Base modified NTPs have been widely used for synthesis of modified mRNA to improve stability and reduce immunogenicity.
ABP Biosciences offers a list of key base modified NTPs for mRNA synthesis.
C...
5-Methyl-CTP (5-Methylcytidine-5'-Triphosphate) is a modified nucleoside triphosphate employed to impart desirable characteristics such as increased nuclease stability, increased translation or reduced interaction of ...
Pseudo-UTP (Pseudouridine-5'-Triphosphate) is one of the most commonly used modified nucleoside-5’-O-triphosphates. Pseudo-UTP is a building block for the polymerase-mediated synthesis of RNA molecules. RNA mole...
N1-Methylpseudo-UTP (N1-Methyl-Pseudouridine-5'-Triphosphate) is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenici...
Lipid Nanoparticles (LNPs) play important role for delivery of mRNA-based vaccines.
ABP Biosciences offers a list of key lipids for formulation of Lipid Nanoparticles (LNPs).
Lipid
...
LNP-0315 is a lipid nanoparticle (LNP) formulated with ALC-0315, DSPC, Cholesterol, and ALC-0159. LNP-0315 is formulated at optimal molar ratio for efficient delivery of mRNA-based vaccines.
L...
LNP-102 is a lipid nanoparticle (LNP) formulated with SM-102, DSPC, Cholesterol, and DMG-PEG2000. LNP-102 is formulated at optimal molar ratio for efficient delivery of mRNA-based vaccines.
LNP-102...
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral phospholipid containing 18:1 fatty acids at the sn–1 and sn–2 positions. The compound displays sensitivity towards pH change. At acid...
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn–1 and sn–2 positions. It has been used in combination...
DMG-PEG(2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Formulations containing DMG-PEG(2000) have been used in the development of lipid ...
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons. It is a&...
ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). ALC-0315 has been used in the development of lipid nanoparticles for delivery of mRN...
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). SM-102 has been used in the development of lipid nanoparticles for delivery of mRNA-ba...
Poly(A), also known as Polyadenylic acid, is used as a carrier for quantitative precipitation of DNA and RNA.
Specifications
Form:
Lyophilized white power
Abs maximum...
The newly identified coronavirus, SARS-CoV-2 (2019-nCoV), has become one of the most contagious disease in human history.
ABP Biosciences offers essential reagents and tools for your exciting coron...