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Transfection Grade PEI (MW 40,000)


The transfection grade polyethylenimine (PEI) is a powerful, trusted, and cost-effective reagent widely considered as a current gold standard for both in vitro and in vivo transfection. PEI has a high density of protonatable amino groups, with amino nitrogen as every third atom. This imparts a high buffering ability at nearly any pH. Hence, once inside the endosome, PEI disrupts the vacuole and releases the genetic material into the cytoplasm. Stable complexation with DNA, efficient entry into the cell, and ability to escape the endosome makes PEI a highly efficient transfection reagent which is compatible for a wide range of cell lines/types including the most commonly used HEK293 and CHO cells grown in adherent and suspension cultures. 


  • Superior Performance: High transfection efficiency with low cytotoxicity.
  • Flexible Workflow: Easy to optimize and introduce into application protocols. Scalable for well plates, flasks, and larger capacity bioreactors.
  • Cost-Effective: Economical compared to similar transfection products in the market.

For research use only.



Appearance: White solid
CAS Number: 49553-93-7
Molecular Formula: (CH2CH2NH•HCl)n
Molecular Weight: average Mn 40000
PDI: <1.3
Storage Condition: 2-8 ℃
Shipping Condition: Room temperature

To order

Buy Cat.No. Product name Size Price
P017-1 PEI 100 mg $95
P017-2 PEI 1 g $400


Product Information (PDF): P017