Introduction To order Documents Related Products Introduction N1-Methylpseudouridine is a modified nucleoside used for enhancing mRNA translation. Incorporation of N1-Methylpseudouridine into mRNA turns off the immune/eIF2α phosphorylation-dependent inhibition of translation, and increases ribosome pausing and density on the mRNA, thus dramatically facilitating the translation process. N1-Methylpseudouridine outperforms several other modified nucleosides (e.g. 5-Methylcytidine) and corresponding combinations […]
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Author Archives: YLQ
mPEG-COOH
Introduction To order Documents Related Products Introduction Methoxypolyethylene glycol carboxyl (mPEG-COOH) are high quality PEG reagents that attach a reactive carboxyl (COOH) group at the terminal site, which can selectively reacts with amino group in the peptide coupling reagent such at NHS, DDC and EDC at pH 7-8. Polyethylene glycol (PEG) compounds are generally biocompatible, non-toxic […]
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MitoView™ Mitochondrial Transition Pore Assay for Flow Cytometry
Introduction To order Documents Related products Introduction The mitochondrion plays a vital role in the processes of apoptotic and necrotic cell death. The mitochondrial permeability transition pore is a nonspecific channel formed by components from the inner and outer mitochondrial membranes, and appears to be involved in the release of mitochondrial components during cell death. […]
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Introduction To order Documents Related products Introduction The mitochondrion plays a vital role in the processes of apoptotic and necrotic cell death. The mitochondrial permeability transition pore is a nonspecific channel formed by components from the inner and outer mitochondrial membranes, and appears to be involved in the release of mitochondrial components during cell death. […]
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iClick™ TUNEL Andy Fluor™ 647 Imaging Assay
Introduction To order Documents Related products Introduction Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-end labeling (TUNEL) method. TUNEL is highly selective for the detection of apoptotic cells but […]
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Introduction To order Documents Related products Introduction Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-end labeling (TUNEL) method. TUNEL is highly selective for the detection of apoptotic cells but […]
Continue Reading iClick™ TUNEL Andy Fluor™ 555 Imaging Assay
Introduction To order Documents Related products Introduction Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-end labeling (TUNEL) method. TUNEL is highly selective for the detection of apoptotic cells but […]
Continue Reading iClick™ TUNEL Andy Fluor™ 488 Imaging Assay
Introduction To order Documents Related products Introduction Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-end labeling (TUNEL) method. TUNEL is highly selective for the detection of apoptotic cells but […]
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Introduction To order Documents Related products Introduction The MitoSOX Red Indicator is a fluorogenic dye for the highly selective detection of superoxide in the mitochondria of live cells. The MitoSOX Red reagent is live-cell permeant which rapidly and selectively target the mitochondria. Once in the mitochondria, the MitoSOX Red reagent is oxidized by superoxide and […]
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iQuant™ microRNA Assay Kit
Introduction To Order Documents Related Products Introduction The iQuant™ microRNA Assay Kit is ideal for quantification of small RNA, including microRNA and siRNA, and both single stranded and double stranded RNA. The assay kit is highly selective for small RNA over rRNA or large mRNA. The assay kit offers advantages in stability, linear dynamic range, and sensitivity over […]
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