5-Methyl-CTP (5-Methylcytidine-5'-Triphosphate) is a modified nucleoside triphosphate employed to impart desirable characteristics such as increased nuclease stability, increased translation or reduced interaction of innate immune receptors with in vitro transcribed RNA. 5-Methyl-CTP, as well as Pseudo-UTP and N1-Methylpseudo-UTP, have been shown to reduce innate immune stimulation in culture and in vivo while enhancing translation in recent publications. 
 
	 
	 
	 
	 
	
	For research use only.
	 

	 
	Technical Information
	 
 
				Formal Name:
			 
				5-Methylcytidine-5'-Triphosphate
			 
 
				CAS Number:
			 
				327174-86-7 (free acid)
			 
 
				Molecular Formula:
			 
				C10H18N3O14P3 (free acid)
			 
 
				Molecular Weight:
			 
				497.18 (free acid)
			 
 
				Purity:
			 
				>95% (HPLC)
			 
 
				Extinction Coefficient:
			 
				8,800 Lmol-1cm-1 at 277 nm
			 
 
				Salt Form:
			 
				Na+
			 
 
				Concentration:
			 
				100 mM in H2O
			 
 
				Storage Condition:
			 
				-20 ℃
			 
 
				Shipping Condition:
			 
				Ice packs
			 
 
								