Dihydrorhodamine 6G is the reduced form of rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide.
Specifications
References:
Ou B, Huang D
Wersto RP, Rosenthal ER, Crystal RG, Spring KR
Moser M, Bauer M, Schmid S, Ruppert R, Schmidt S, Sixt M, Wang HV, Sperandio M, Fässler R,
Label:
Rhodamine 6G
Ex/Em:
528/551 nm
Detection Method:
Fluorescent
Solubility:
DMSO, DMF
Molecular Formula:
C28H32N2O3
Molecular Weight:
444.57
CAS Number:
217176-83-5
Storage Conditions:
-20 ℃, protect from light
Shipping Condition:
Room Temperature
Applications
Probe for ROS
Datasheet (PDF):
C262
MSDS (PDF):
MSDS-C262
Anal Chem (2006) 78:3097-3103
Proc Natl Acad Sci U S A (1996) 93:1167-1172
Nat Med (2009) 15:300-305