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Biotin Azide


Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moieties to label and detect a molecule of interest in mild, aqueous conditions. The click reaction involves a copper-catalyzed triazole formation from an azide and an alkyne. The azide and alkyne moieties can be used interchangeably; either one can be used to tag the molecule of interest, while the other is used for subsequent detection.
The biotin azide is reactive with terminal alkyne via a copper-catalyzed click reaction. Biotin can be subsequently detected with streptavidin, avidin or NeutrAvidin® biotin-binding protein.


  • Efficiency—the click reaction is complete in less than 1 hour;
  • Specificity—the reaction between the label and detection tag is selective and specific;
  • Stability—the reaction product contains an irreversible, covalent bond;
  • Biologically inert—the components of the reaction do not undergo any side reactions.

Figure 1. Click chemistry labeling


Label: Biotin
Detection Method:
Solubility: DMSO, DMF
Molecular Weight: 400.50
Product Size: 5 mg
Storage Conditions: -20 ℃, protect from light
Shipping Condition: Room Temperature

Click chemistry labeling


To order

Buy Cat.No. Product Name Ex/Em(nm) Unit Price
C304 Biotin Azide 5 mg $100


Datasheet (PDF): C304
MSDS (PDF): C304


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Angew Chem Int Ed Engl (2009) 48:4030-4033

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