• YLQ
• Cell Apoptosis Assay, Product
• Aug, 27, 2015
• Comments Off on TUNEL assays

Introduction To Order Related products Introduction The later stages of apoptosis are characterized by changes in nuclear morphology, including DNA fragmentation, chromatin condensation, degradation of nuclear envelope, nuclear blebbing, and DNA strand breaks. DNA fragmentation that occurs during apoptosis produces DNA strand breaks, which can be analyzed using TUNEL (terminal deoxynucleotidyl transferase dUTP nick end-labeling) […]

• YLQ
• Cell Apoptosis Assay, Product
• Aug, 27, 2015
• Comments Off on Mitochondrial Membrane Potential Assays

Introduction To order Related products Introduction A distinctive feature of the early stages of apoptosis is the disruption of active mitochondria, including changes in membrane potential and alterations to redox potential. JC-1 (5,5’,6,6’-tetrachloro-1,1’,3,3’-tetraethylbenzimidazolylcarbocyanine iodide) is a novel cationic carbocyanine dye. In healthy cells, JC-1 selectively accumulates in mitochondria and forms J-aggregates that exhibit red fluorescence. […]

• YLQ
• Cell Apoptosis Assay, Product
• Aug, 27, 2015
• Comments Off on JC-1 Mitochondrial Membrane Potential Detection Kit

Introduction To order Documents Related products Introduction JC-1 Mitochondrial Membrane Potential Detection Kit provides a quick and reliable method to detect the mitochondrial membrane potential changes in apoptotic cells using flow cytometry. The loss of mitochondrial membrane potential is a hallmark for apoptosis. The JC-1 Assay Kit uses a unique cationic dye (5,5’,6,6’- tetrachloro-1,1’,3,3’-tetraethylbenzimidazolylcarbocyanine iodide) to signal […]

• YLQ
• Cell Apoptosis Assay, Product
• Aug, 26, 2015
• Comments Off on Caspase-3/7 Inhibitor Ac-DEVD-CHO

Introduction To order Documents Related products Introduction Ac-DEVD-CHO is a synthetic tetrapeptide competitive inhibitor for caspase-3/7. It contains the amino acid sequence of the PARP cleavage site. Ac-DEVD-CHO can be used to inhibitor caspase-3/7 activity in apoptotic cells, and to study events downstream of caspase-3/7 activation.   Substrate Specifications Substrate name: Ac-DEVD-CHO Molecular weight: 502.5 […]

• YLQ
• Cell Apoptosis Assay, Product
• Aug, 26, 2015
• Comments Off on Caspase-3/7 Substrate Z-DEVD-R110

Introduction To order Documents Related products Introduction The caspase-3/7 substrate is a bisamide derivative of the fluorophore rhodamine 110 (R110). Peptides are covalently linked to each of the amino groups of rhodamine 110 (R110), thereby suppressing both the visible absorption and fluorescence of the dye. Upon enzymatic cleavage, the nonfluorescent bisamide substrate is converted in […]

• YLQ
• Cell Apoptosis Assay, Product
• Aug, 01, 2015
• Comments Off on Caspase-3/7 Z-DEVD-R110 Assay Kit

Introduction To order Documents Related products Introduction The Caspase-3/7 Z-DEVD-R110 Assay Kit provides a method for detecting apoptosis by providing a simple and reliable method for assaying caspase-3/7 activity. The kit can be used to continuously measure the activity of caspase-3/7 in cell extracts and purified enzyme preparations, using a fluorometer or fluorescence microplate reader. The rhodamine […]

• YLQ
• Cell Apoptosis Assay, Product
• Aug, 01, 2015
• Comments Off on Caspase Activity Assays

Introduction To Order Related Products Introduction A distinctive feature of the early stages of apoptosis is the activation of caspase enzymes, which participate in the cleavage of protein substrates and in the subsequent disassembly of the cell. ABP Biosciences offer a series of caspase assays that allow the simple detection of active caspases in living cells in […]