MitoSOX Red

The MitoSOX Red Indicator is a fluorogenic dye for the highly selective detection of superoxide in the mitochondria of live cells. The MitoSOX Red reagent is live-cell permeant which rapidly and selectively target the mitochondria. Once in the mitochondria, the MitoSOX Red reagent is oxidized by superoxide and exhibit bright red fluorescence. The production of superoxide by mitochondria can be visualized in fluorescence microscopy. The MitoSOX Red reagent is readily oxidized by superoxide but not by other reactive oxygen species (ROS) and reactive nitrogen species (RNS).